
段金菊
女,,57歲,,漢族,中國(guó)共產(chǎn)黨黨員,,山西醫(yī)科大學(xué)第二醫(yī)院藥學(xué)部副主任,,主任藥師,,博士,博士生導(dǎo)師,。
E-mail:[email protected]
教育經(jīng)歷
2016.12.10-12.18 美國(guó)約翰霍普金斯大學(xué)藥學(xué)研修
2004.09-2007.07 山西醫(yī)科大學(xué) 內(nèi)科學(xué)博士
1999.09-2002.07 山西醫(yī)科大學(xué) 藥理學(xué)碩士
1984.09-1988.07 天津第二醫(yī)學(xué)院 藥學(xué)學(xué)士
工作經(jīng)歷
至今山西醫(yī)科大學(xué)藥學(xué)院客座教授
2010.5-至今山西醫(yī)科大學(xué)第二醫(yī)院主任藥師
2003.5-2010.4山西醫(yī)科大學(xué)第二醫(yī)院副主任藥師
1998.5-2003.4山西醫(yī)科大學(xué)第二醫(yī)院主管藥師
1988.5-1998.4山西醫(yī)科大學(xué)第二醫(yī)院藥師
學(xué)術(shù)任職
《中國(guó)醫(yī)院藥學(xué)雜志》編委;《山西醫(yī)科大學(xué)學(xué)報(bào)》編委;《中國(guó)臨床藥理學(xué)》青年編委; 山西醫(yī)科大學(xué)兼職教授; 山西省學(xué)術(shù)技術(shù)帶頭人; 山西省“三晉英才”拔尖骨干人材,。
社會(huì)兼職:國(guó)家藥事管理專(zhuān)業(yè)質(zhì)控中心專(zhuān)家委員會(huì)成員;中國(guó)醫(yī)院協(xié)會(huì)藥事管理專(zhuān)業(yè)委員會(huì)常務(wù)委員;中國(guó)藥學(xué)會(huì)抗生素專(zhuān)業(yè)委員會(huì)委員;全國(guó)抗真菌病監(jiān)測(cè)網(wǎng)質(zhì)量管理中心委員;全國(guó)抗菌藥物監(jiān)測(cè)網(wǎng)及真菌病監(jiān)測(cè)網(wǎng)山西分網(wǎng)負(fù)責(zé)人;全國(guó)老年藥學(xué)聯(lián)盟常務(wù)理事;山西省醫(yī)學(xué)會(huì)微生物與免疫學(xué)專(zhuān)業(yè)委員會(huì)主任委員;山西省藥師協(xié)會(huì)合理用藥分會(huì)主任委員;山西省衛(wèi)生廳醫(yī)療質(zhì)量控制中心藥事質(zhì)控部副主任,;山西省醫(yī)學(xué)會(huì)臨床藥學(xué)專(zhuān)業(yè)委員會(huì)副主任委員,。
榮譽(yù)獲獎(jiǎng)
先后承擔(dān)了省級(jí)科研課題6項(xiàng),以主持人獲山西省科技進(jìn)步二等獎(jiǎng),、三等獎(jiǎng)各一項(xiàng),。
教學(xué)情況
2006年起協(xié)助指導(dǎo)研究生12名,2010年起至今指導(dǎo)研究生共30名,。
2019年至今講授臨床藥學(xué)本科課程--臨床藥理學(xué),。
研究領(lǐng)域
現(xiàn)主要從事細(xì)菌耐藥機(jī)制研究和藥物基因組學(xué)研究,先后承擔(dān)了省級(jí)科研課題6項(xiàng),。以第一作者和通訊作者發(fā)表論文70余篇,,其中SCI 20多篇,。
代表性科研、教改項(xiàng)目
1,、同種異體骨軟骨移植生物安全保障體系的構(gòu)建,,中華人民共和國(guó)科學(xué)技術(shù)部國(guó)家重點(diǎn)研發(fā)計(jì)劃,2024,,150萬(wàn)元
2,、有機(jī)合成分子MTEBT-3對(duì)碳青霉烯類(lèi)耐藥的肺炎克雷伯菌(CRKP)抗耐藥、抗毒力和破膜機(jī)制的研究,,山西省科技廳,,2024,8萬(wàn)元
3、建立三級(jí)基層藥學(xué)服務(wù)規(guī)范,,保障基層慢病患者用藥安全,,基層適宜性技術(shù)推廣項(xiàng)目,202305,5萬(wàn)元
4,、吳階平醫(yī)學(xué)基金,,320.6750.2021-08-8,電荷可控納米脂質(zhì)體藥物對(duì)抗銅綠假單胞菌生物膜引起的廣泛耐藥研究,,2021.10-2023.10,,5萬(wàn)元,在研,,主持
5,、山西省科學(xué)技術(shù)廳自然科學(xué)基金,201901D111390,,神經(jīng)外科術(shù)后中樞神經(jīng)系統(tǒng)感染病原學(xué)流行病學(xué)及抗菌藥物的PK/PD研究,,2019.9-2022.9,5萬(wàn)元,,在研,,主持
6、山西地區(qū)碳青霉烯類(lèi)耐藥的肺炎克雷伯菌分子流行病學(xué)特點(diǎn)及治療對(duì)策研究,,山西省科學(xué)技術(shù)廳社會(huì)發(fā)展項(xiàng)目,,項(xiàng)目編號(hào)201803D31124
7、喹諾酮類(lèi)藥物對(duì)銅綠假單胞菌生物膜喹諾酮信號(hào)(PQS)系統(tǒng)的機(jī)制研究,,山西省科學(xué)技術(shù)廳自然科學(xué)基金,,項(xiàng)目編號(hào)201601D11113
8、血糖水平對(duì)銅綠假單胞菌生物膜形成影響的研究,,山西省衛(wèi)生廳科技攻關(guān)項(xiàng)目,,項(xiàng)目編號(hào)2014045
代表性論著
Anti-bacteria, anti-biofilm, and anti-virulence activity of the synthetic compound MTEBT-3 against carbapenem-resistant Klebsiella pneumoniae strains ST3984,2024,IF=3.3(通訊作者)
Dual osmotic controlled release platform for antibiotics to overcome antimicrobial-resistant infections and promote wound healing,2024,IF=10.5(共同通訊作者)
Characteristics, Outcomes, and Clinical Indicators of Bloodstream Infections in Neutropenic Patients with Hematological Malignancies: A 7-Year Retrospective Study,2023,IF=2.9(通訊作者)
Molecular Epidemiology of Carbapenem Resistant Klebsiella pneumoniae in Northern China: Clinical Characteristics, Antimicrobial Resistance, Virulence and Geographic Distribution,2023,IF=2.9(通訊作者)
Prevalence of antimicrobial use and healthcare-associated infections in China: Results from the first point prevalence survey in 18 hospitals in Shanxi Province, 2023,IF=3.7(通訊作者)
Antibiotic resistance and virulence characteristics of four carbapenem-resistant Klebsiella pneumoniae strains coharbouring blaKPC and blaNDM based on whole genome sequences from a tertiary general teaching hospital in central China between 2019 and 2021, 2023, IF=3.3(通訊作者)
Moderating effects of humanistic care and socioeconomic status on the relationship among pain intensity, psychological factors, and psychological function in adults with cancer pain from a province of China: A cross-sectional study, 2023, IF=3.2(通訊作者)
Bacteriological Profile and Antimicrobial Susceptibility Patterns of Gram-Negative Bloodstream Infection and Risk Factors Associated with Mortality and Drug Resistance: A Retrospective Study from Shanxi, China, 2022, IF=2.9(通訊作者)
Mortality Risk Factors and Prognostic Analysis of Patients with Multi-Drug Resistant Enterobacterales Infection, 2022, IF=2.9(通訊作者)
Three Novel Sequence Types Carbapenem-Resistant Klebsiella pneumoniae Strains ST5365, ST5587, ST5647 Isolated from Two Tertiary Teaching General Hospitals in Shanxi Province, in North China: Molecular Characteristics, Resistance and Virulence Factors, 2022, IF=2.9(通訊作者)
Epidemiology of patients with central nervous system infections, mainly neurosurgical patients: a retrospective study from 2012 to 2019 in a teaching hospital in China, 2021(通訊作者)
Co-Production of NDM-1, CTX-M-9 Family and mcr-1 in a Klebsiella pneumoniae ST4564 Strain in China, 2021(通訊作者)
Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population, 2020(通訊作者)
Emergence of NDM-5-Producing Carbapenem Resistant Klebsiella pneumoniae and SIM-Producing Hypervirulent Klebsiella pneumoniae Isolated from Aseptic Body Fluid in a Large Tertiary Hospital, 2017–2018: Genetic Traits of blaNDM-Like and blaSIM-Like Genes as Determined by NGS, 2020(通訊作者)
Successful control of the first carbapenemresistant Klebsiella pneumoniae outbreak in a Chinese hospital 2017–2019, 2020(通訊作者)
The role of clinical pharmacist trainees in medication reconciliation process at hospital admission, 2020(通訊作者)
The effect of inpatient pharmaceutical care on nephrotic syndrome patients after discharge: a randomized controlled trial, 2020(通訊作者)